Antibacterial Coatings Based on Chitosan for Pharmaceutical and Biomedical Applications
نویسندگان
چکیده
منابع مشابه
Chitosan Modification and Pharmaceutical/Biomedical Applications
Chitosan has received much attention as a functional biopolymer for diverse applications, especially in pharmaceutics and medicine. Our recent efforts focused on the chemical and biological modification of chitosan in order to increase its solubility in aqueous solutions and absorbability in the in vivo system, thus for a better use of chitosan. This review summarizes chitosan modification and ...
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Chitosan is a natural polycationic linear polysaccharide derived from chitin. The low solubility of chitosan in neutral and alkaline solution limits its application. Nevertheless, chemical modification into composites or hydrogels brings to it new functional properties for different applications. Chitosans are recognized as versatile biomaterials because of their non-toxicity, low allergenicity...
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In a marine environment, specific proteins are secreted by mussels and used as a bioglue to stick to a surface. These mussel proteins present an unusual amino acid 3,4-dihydroxyphenylalanine (known as DOPA). The outstanding adhesive properties of these materials in the sea harsh conditions have been attributed to the presence of the catechol groups present in DOPA. Inspired by the structure and...
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Chitosan-one of the natural multifunctional polymers-due to its unique and versatile biological properties is regarded as a useful compound in medical and pharmaceutical technology. Recently, considerable research effort has been made in order to develop safe and efficient chitosan products. However, the problem of poor stability of chitosan-based systems restricts its practical applicability; ...
متن کاملChitosan coating as an antibacterial surface for biomedical applications
BACKGROUND AND OBJECTIVES A current public health issue is preventing post-surgical complications by designing antibacterial implants. To achieve this goal, in this study we evaluated the antibacterial activity of an animal-free chitosan grafted onto a titanium alloy. METHODS Animal-free chitosan binding on the substrate was performed by covalent link via a two-step process using TriEthoxySil...
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ژورنال
عنوان ژورنال: Current Pharmaceutical Design
سال: 2018
ISSN: 1381-6128
DOI: 10.2174/1381612824666180219143900